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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK25
All Species:
25.76
Human Site:
T234
Identified Species:
47.22
UniProt:
O00506
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00506
NP_006365.2
426
48112
T234
I
P
K
N
S
P
P
T
L
E
G
Q
H
S
K
Chimpanzee
Pan troglodytes
XP_001162228
584
64501
T392
I
P
K
N
S
P
P
T
L
E
G
Q
H
S
K
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
T243
I
P
T
N
P
P
P
T
F
R
K
P
E
L
W
Dog
Lupus familis
XP_848578
318
35396
P134
M
R
V
L
F
L
I
P
K
N
S
P
P
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2W1
426
48157
T234
I
P
K
N
N
P
P
T
L
E
G
H
H
S
K
Rat
Rattus norvegicus
O54748
491
56103
T240
I
P
T
N
P
P
P
T
F
R
K
P
E
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513191
426
48196
T234
I
P
K
N
N
P
P
T
L
E
G
H
H
S
K
Chicken
Gallus gallus
Q5ZJK4
486
55318
T242
I
P
T
N
P
P
P
T
F
R
K
P
E
L
W
Frog
Xenopus laevis
Q6IP06
493
56486
T239
I
P
T
N
P
P
P
T
F
R
K
P
E
L
W
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
T239
I
P
T
N
P
P
P
T
F
R
K
P
E
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
S255
I
P
Q
K
P
P
P
S
F
R
E
P
D
R
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
T248
I
P
T
K
P
P
P
T
F
K
K
P
E
E
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38692
1080
117043
R239
I
I
K
S
K
P
P
R
L
E
D
R
S
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.4
38.4
71.5
N.A.
98.5
38.4
N.A.
94.3
38.8
38.5
38.6
N.A.
29.7
N.A.
35.6
N.A.
Protein Similarity:
100
72.5
57
72.5
N.A.
99.7
55.1
N.A.
97.8
55.9
56.1
56.9
N.A.
42.1
N.A.
51.7
N.A.
P-Site Identity:
100
100
40
0
N.A.
86.6
40
N.A.
86.6
40
40
40
N.A.
26.6
N.A.
33.3
N.A.
P-Site Similarity:
100
100
40
13.3
N.A.
93.3
40
N.A.
93.3
40
40
40
N.A.
40
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
28.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
39
8
0
47
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
54
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
16
31
8
0
% H
% Ile:
93
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
39
16
8
0
0
0
8
8
47
0
0
0
31
% K
% Leu:
0
0
0
8
0
8
0
0
39
0
0
0
0
31
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
70
16
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
85
0
0
54
93
93
8
0
0
0
62
8
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
16
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
8
0
47
0
8
0
8
0
% R
% Ser:
0
0
0
8
16
0
0
8
0
0
8
0
8
31
8
% S
% Thr:
0
0
47
0
0
0
0
77
0
0
0
0
0
8
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _